A shuttle is a vehicle or aircraft that travels regularly between two places.

A space shuttle is a reusable spacecraft designed to transport people and cargo between Earth and space.

Spaceflight I

Spaceflight (or space flight) applies astronautics to fly spacecraft into or through outer space, either with or without humans on board. Most spaceflight is uncrewed and conducted mainly with spacecraft such as satellites in orbit around Earth and includes space probes for flights beyond Earth orbit. Such spaceflight operates either by telerobotic or autonomous control.